The positive impact of the liberalization of air transport, largely supported by the economic theory and "validated" by the empirical studies, has inspired many developing countries to liberalize some of their Air Service Agreements (ASA). After Nigeria and Morocco, Tunisia has signed in December 11th, 2017 the agreement of Open Sky with the European Union (EU), its historic economic partner. Thus, the Tunisian airlines will be exposed to key issues emanating from both the agreement and the activation of the Yamoussoukro Declaration signed more than 15 years ago. Given these potential deep conditioning mutations, in the future Tunisian air transport, this paper will attempt to predict and compare the dynamics of air demand in Tunisia from the initiation of both agreements. The aim of our work is to qualify the effects of the Tunisian-EU Open Sky and Yamoussoukro agreement based on the reproduction of passenger traffic Reference situation marked by its restrictive character, using macroeconomic factors (trade and GDP), the distance and the ASA liberalization indicator to build our econometric model. The comparison will be justified by a working simulation of various liberalization options.