[ Diagnostic cytologique des maladies de surcharges: Expérience du laboratoire d’Hématologie Centre Hospitalier Universitaire Ibn Rochd de Casablanca ]
Volume 38, Issue 1, November 2022, Pages 146–150
Rachid Elfaiz1, Hanae Bencharef2, and Bouchra Oukkache3
1 Laboratoire de biochimie, CHU Ibn Rochd de Casablanca, Morocco
2 Hematology Laboratory, Ibn Rochd University Hospital of Casablanca, Morocco
3 Hematology Laboratory, Ibn Rochd University Hospital of Casablanca, Morocco
Original language: French
Copyright © 2022 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The lysosomal overload diseases constitute a heterogeneous group of rare constitutional diseases. In Morocco, these diseases remain very rare and under diagnosed. The diagnosis of certainty rests on enzymatic assay which can be long and difficult, unlike the discovery of a cytological anomaly thus allowing a fast tracking and early care management, hence the importance of the study of these pathologies at pediatric age and the installation of a register of rare pathologies. This present work aims to describe four clinico-biological observations of the overload diseases diagnosed in our laboratory.
Author Keywords: Overload disease, Gaucher histiocyte, lysosomal, Niemann-Pick disease, Gaucher disease.
Volume 38, Issue 1, November 2022, Pages 146–150
Rachid Elfaiz1, Hanae Bencharef2, and Bouchra Oukkache3
1 Laboratoire de biochimie, CHU Ibn Rochd de Casablanca, Morocco
2 Hematology Laboratory, Ibn Rochd University Hospital of Casablanca, Morocco
3 Hematology Laboratory, Ibn Rochd University Hospital of Casablanca, Morocco
Original language: French
Copyright © 2022 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The lysosomal overload diseases constitute a heterogeneous group of rare constitutional diseases. In Morocco, these diseases remain very rare and under diagnosed. The diagnosis of certainty rests on enzymatic assay which can be long and difficult, unlike the discovery of a cytological anomaly thus allowing a fast tracking and early care management, hence the importance of the study of these pathologies at pediatric age and the installation of a register of rare pathologies. This present work aims to describe four clinico-biological observations of the overload diseases diagnosed in our laboratory.
Author Keywords: Overload disease, Gaucher histiocyte, lysosomal, Niemann-Pick disease, Gaucher disease.
Abstract: (french)
Les maladies de surcharge lysosomale (MSL) constituent un groupe hétérogène de maladies constitutionnelles rares. Au Maroc ces maladies restent très rares et sous diagnostiquées. Le diagnostic de certitude repose sur le dosage enzymatique qui peut être long et difficile, contrairement à la découverte d’une anomalie cytologique permettant ainsi un dépistage rapide et prise en charge précoce, d’où l’importance de l’étude de ces pathologies à l’âge pédiatrique et la mise en place d’un registre de pathologies rares. Ce présent travail a pour objectif de décrire quatre observations, clinico-biologiques des maladies de surcharges diagnostiquées au sein de notre laboratoire.
Author Keywords: Maladie de surcharge, Histiocyte de Gaucher, Histiocyte vacuolé, lysosomale, Maladie Niemann-Pick, Maladie de gaucher.
How to Cite this Article
Rachid Elfaiz, Hanae Bencharef, and Bouchra Oukkache, “Cytological diagnosis of overload diseases: Experience of the hematology laboratory of the Ibn Rochd University Hospital of Casablanca,” International Journal of Innovation and Applied Studies, vol. 38, no. 1, pp. 146–150, November 2022.
