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International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
 
 
Wednesday 19 June 2019

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Restoration of the glycoconjugates expression in the ventral prostate of androgen-deprived mice by dihydrotestosterone: A glycohistochemical study


Volume 16, Issue 1, May 2016, Pages 19–24

 Restoration of the glycoconjugates expression in the ventral prostate
of androgen-deprived mice by dihydrotestosterone: A glycohistochemical study

Fouad AKIF1 and Franck Genten2

1 Centre Régional des Métiers d’Education et de Formation (CRMEF) Souss Massa Darea, Morocco
2 Laboratoire de Biopathologie Vétérinaire, Faculté de Médecine, Université Libre de Bruxelles, Belgium

Original language: English

Received 29 February 2016

Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


We investigated histochemically the expression of glycans in the mouse ventral prostate of the normal, castrated, castrated mice injected with testosterone (T) and castrated mice injected with dihydrotestosterone (DHT). The avidin-biotin-peroxidase complex technique was used with eight biotinylated lectins, on paraffin sections. Remarkably, contrarily to T, the DHT found to restore all the glycans in epithelial cells of ventral prostate. The histophysiological significance of the activation synthesis of glycoconjugates in mouse ventral prostate by DHT is discussed in the light of the other studies obtained mainly in humans.

Author Keywords: Ventral prostate, lectins, Testosterone, Dihydrotestosterone, Glycohistochemistry.


How to Cite this Article


Fouad AKIF and Franck Genten, “Restoration of the glycoconjugates expression in the ventral prostate of androgen-deprived mice by dihydrotestosterone: A glycohistochemical study,” International Journal of Innovation and Applied Studies, vol. 16, no. 1, pp. 19–24, May 2016.