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International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
 
 
Friday 25 May 2018

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  Call for Papers - May 2018     |     Now IJIAS is indexed in EBSCO, ResearchGate, ProQuest, Chemical Abstracts Service, Index Copernicus, IET Inspec Direct, Ulrichs Web, Google Scholar, CAS Abstracts, J-Gate, UDL Library, CiteSeerX, WorldCat, Scirus, Research Bible and getCited, etc.  
 
 
 

Synthesis of new derivatives pyridazinones assisted by Microwave on dry medium comparing it to conventional heating (refluxing)


[ Synthèse de nouveaux dérivés pyridazinones assistée par Micro-ondes en milieu sec en le comparant au chauffage classique (chauffage à reflux) ]

Volume 18, Issue 2, October 2016, Pages 381–387

 Synthesis of new derivatives pyridazinones assisted by Microwave on dry medium comparing it to conventional heating (refluxing)

Ahmad Oubair1 and Rachid Fihi2

1 Département de chimie, Université My Smail Meknes, Faculté des Sciences et Technique, Errachidia, Morocco
2 Département de chimie, Université My Smail Meknes, Faculté des Sciences et Technique, Errachidia, Morocco

Original language: French

Received 16 June 2016

Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


In this work, we report an efficient protocol containing the technique of microwave oven and its comparison with the conventional method (refluxing) for the synthesis of new derivatives pyridazinones namely 4-(p-alkylbenzylidene)pyridazin-3(2H)-ones. These are obtained by condensation of α-arylidene-γ-butyrolactones precursors and hydrazines in the presence of p-toluene sulfonic acid (PTSA). The structures of these new compounds were identified by spectral methods (1H, 13C NMR and IR).

Author Keywords: α-arylidene-γ-butyrolactone, hydrazine, pyridazinones, microwave, silice.


Abstract: (french)


Dans ce travail, nous rapportons un protocole efficace contenant la technique du four à micro-ondes et sa comparaison à la méthode classique (chauffage à reflux) pour la synthèse de nouveaux dérivés pyridazinones à savoir 4-(p-alkylbenzylidène)pyridazin-3(2H)-ones. Ces derniers sont obtenus par condensation des précurseurs α-arylidène-γ-butyrolactones et les hydrazines en présence de l’acide p-toluène sulfonique (APTS). Les structures des produits synthétisés ont été établies à l’aide des analyses spectroscopiques, RMN 1H, 13C et IR.

Author Keywords: α-arylidène-γ-lactones, hydrazines, pyridazinones, micro-ondes, silice.


How to Cite this Article


Ahmad Oubair and Rachid Fihi, “Synthesis of new derivatives pyridazinones assisted by Microwave on dry medium comparing it to conventional heating (refluxing),” International Journal of Innovation and Applied Studies, vol. 18, no. 2, pp. 381–387, October 2016.