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International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
 
 
Thursday 15 November 2018

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Inhibition de la cristallisation in vitro de l'oxalate de calcium par extrait aqueux de Zizyphus Lotus


Volume 23, Issue 4, July 2018, Pages 583–589

 Inhibition de la cristallisation in vitro de l'oxalate de calcium par extrait aqueux de Zizyphus Lotus

Latifa Baddade1, Mustapha El Bir2, M. Oubenali3, Malika Echajia4, Souad Rabi5, Mohamed Berkani6, and Mohamed Mbarki7

1 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
2 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
3 Transdisciplinary Team of Analytical Science for Sustainable Development, University Sultan Moulay Slimane, Béni Mellal, Morocco
4 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Béni Mellal, Morocco
5 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Béni Mellal, Morocco
6 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
7 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Beni Mellal, Morocco

Original language: French

Received 25 May 2018

Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


In the context of sustainable development and promoting natural resources, some forgotten fruits such as the Zizyphus Lotus can be developed as local products. In addition, the frequency of Urolithiasis multiplied increasingly rapidly in the world. The Urolithiasis involves the formation of crystalline aggregates called "urinary stones" developed in the urinary tract, usually in the kidneys or ureters, but may also affect the bladder or urethra. The objective of this study is to study in vitro the crystallization of calcium oxalate as a lithogenic species and to investigate the inhibitory effect of aqueous jujube extracts on the crystallization of calcium oxalate in order to exploit it. Six jujube fruit samples were taken from six geographical zones from Beni Mellal-Khenifra region. These fruit - seed samples were separated from their seeds. The pulps were subjected to a grinding mortar so as to have fine powder. The samples have been subsequently, submitted a cold maceration during 48 hours. The study of the crystallization of calcium oxalate is carried out by the optical microscope with polarized light (MLP). Some aqueous extracts have an anti-lithiasic effect on the aqueous solution of the lithogenous species studied.

Author Keywords: Urolithiasis, calcium oxalate, crystallization, PLM, valorization, Zizyphus Lotus, anti-lithiasic effect.


Abstract: (french)


Dans le contexte du développement durable et de la valorisation des ressources naturelles, certains fruits dits oubliés comme le cas de Zizyphus Lotus peut être développés en tant que produits locaux. En outre, la fréquence d’urolithiase augmente de plus en plus dans le monde. L'urolithiase consiste à la formation des agrégats cristallins appelés « pierres urinaires » développés dans l'appareil urinaire, habituellement dans les reins ou les uretères, mais peut également affecter la vessie ou l'urètre. L’objectif de cette étude est d’étudier la cristallisation in vitro d'oxalate de calcium comme espèce lithogène et de chercher l'effet inhibiteur des extraits aqueux du jujube sur la cristallisation de l'oxalate de calcium pour le valoriser. Six échantillons de fruits de jujube ont été prélevés sur six zones géographiques de la région de Béni Mellal-Khenifra. Ces échantillons fruits - graines ont été séparés de leurs graines. Les pulpes ont été broyées à l’aide d’un mortier de façon à avoir une poudre fine. Les échantillons par la suite ont été soumis à une macération à froid pendant 48 heures. L'étude de la cristallisation de l'oxalate de calcium est réalisée grâce au microscope optique à lumière polarisé (MLP). Certains extraits aqueux présentent un effet anti- lithiasique sur la solution aqueuse de l’espèce lithogène étudié.

Author Keywords: Urolithiase, oxalate de calcium, cristallisation, MLP, valorisation, Zyziphus Lotus, effet anti-lithiasique.


How to Cite this Article


Latifa Baddade, Mustapha El Bir, M. Oubenali, Malika Echajia, Souad Rabi, Mohamed Berkani, and Mohamed Mbarki, “Inhibition de la cristallisation in vitro de l'oxalate de calcium par extrait aqueux de Zizyphus Lotus,” International Journal of Innovation and Applied Studies, vol. 23, no. 4, pp. 583–589, July 2018.