Volume 24, Issue 4, November 2018, Pages 1819–1822
Abdeslam Ansari1, Ahmad Oubair2, and M. Znini3
1 Laboratory of Natural Substances & Synthesis and Dynamics Molecular, Moulay Ismail University Meknes, Faculty of Sciences and Technics, Errachidia, Morocco
2 Département de chimie, Université My Smail Meknes, Faculté des Sciences et Technique, Errachidia, Morocco
3 Laboratoire des Substances Naturelles & Synthèse et Dynamique Moléculaire, Faculté des Sciences et Techniques, Université Moulay Ismail, Errachidia, Morocco
Original language: English
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Menthone, is a monoterpene ketone, occurs in nature and widely present in high concentration in mentha species essential oils. Also, it has become the key to the synthesis of many heterocyclic compounds exhibiting various kinds of biological activity. The objective of the present work is to synthesize new menthone derivative compounds such as menthopyrazole (HPM) and 1-phenylmenthopyrazole (PMP) by condensation of hydroxymethylenementhone with hydrazine and phenylhydrazine, respectively. The structures of these compounds were characterized by FT-IR, 1H NMR and 13C NMR spectra.
Author Keywords: Menthone, Hydroxymethylenementhone, Menthopyrazole, Hydrazine, Phenylhydrazine.
Abdeslam Ansari1, Ahmad Oubair2, and M. Znini3
1 Laboratory of Natural Substances & Synthesis and Dynamics Molecular, Moulay Ismail University Meknes, Faculty of Sciences and Technics, Errachidia, Morocco
2 Département de chimie, Université My Smail Meknes, Faculté des Sciences et Technique, Errachidia, Morocco
3 Laboratoire des Substances Naturelles & Synthèse et Dynamique Moléculaire, Faculté des Sciences et Techniques, Université Moulay Ismail, Errachidia, Morocco
Original language: English
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Menthone, is a monoterpene ketone, occurs in nature and widely present in high concentration in mentha species essential oils. Also, it has become the key to the synthesis of many heterocyclic compounds exhibiting various kinds of biological activity. The objective of the present work is to synthesize new menthone derivative compounds such as menthopyrazole (HPM) and 1-phenylmenthopyrazole (PMP) by condensation of hydroxymethylenementhone with hydrazine and phenylhydrazine, respectively. The structures of these compounds were characterized by FT-IR, 1H NMR and 13C NMR spectra.
Author Keywords: Menthone, Hydroxymethylenementhone, Menthopyrazole, Hydrazine, Phenylhydrazine.
How to Cite this Article
Abdeslam Ansari, Ahmad Oubair, and M. Znini, “Synthesis and Characterization of new Menthopyrazole Compounds derived from Menthone,” International Journal of Innovation and Applied Studies, vol. 24, no. 4, pp. 1819–1822, November 2018.
