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International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
 
 
Monday 28 November 2022

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Predictive factors of the response to intravenous corticosteroid therapy in severe acute colitis


[ Facteurs prédictifs de la réponse à la corticothérapie intraveineuse au cours des colites aigues graves ]

Volume 29, Issue 4, July 2020, Pages 1027–1029

 Predictive factors of the response to intravenous corticosteroid therapy in severe acute colitis

S. Ouahid1, Sanaa Berrag2, I. Radouane3, F. Nejjari4, T. Addioui5, Mouna Tamzaourte6, and Aziz Aourarh7

1 Service de Gastroentérologie clinique, Hôpital Militaire d’Instructions Mohammed V, Rabat, Morocco
2 Department of Gastroenterology, Military Hospital Mohammed V, Rabat, Morocco
3 Service de Gastroentérologie clinique, Hôpital Militaire d’Instructions Mohammed V, Rabat, Morocco
4 Service de Gastroentérologie clinique, Hôpital Militaire d’Instructions Mohammed V, Rabat, Morocco
5 Service de Gastroentérologie clinique, Hôpital Militaire d’Instructions Mohammed V, Rabat, Morocco
6 Department of Gastroenterology, Military Hospital Mohammed V, Rabat, Morocco
7 Department of Gastroenterology, Military Hospital Mohammed V, Rabat, Morocco

Original language: French

Copyright © 2020 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


Severe acute colitis is a medical and surgical emergency that involves the short-term life threatening. The diagnosis of CAG is based on the combination of clinical and biological criteria and can be supported by morphological criteria (endoscopy, scanner). It complicates ulcerative colitis (UC) as well as Crohn's disease.It is a serious complication which, in the absence of proper care, in a specialized environment, is likely to jeopardize the vital prognosis. Intravenous corticosteroid therapy (CO IV) is the first-line medical treatment for AGC.The objective of our work is to assess the predictive factors of the response to intravenous corticosteroid therapy during severe acute colitis. This is an observational study spread over 2 years, covering 27 cases of severe acute colitis collected within our department. The Severe acute colitis was defined by a Lichtiger score greater than 10. Clinical, biological, endoscopic and radiological data were collected and analyzed by SPSS20 software.

Author Keywords: Severe acute colitis, chronic inflammatory bowel disease, ulcerative colitis, Crohn, treatment.


Abstract: (french)


La colite aigue grave (CAG) est une urgence médico-chirurgicale qui met en jeu le pronostic vital à court terme. Le diagnostic de CAG repose sur l’association de critères clinico-biologiques et peut être étayé́ par des critères morphologiques (endoscopie, scanner). Elle complique aussi bien la rectocolite hémorragique (RCH) que la maladie de Crohn.Il s’agit d’une complication grave qui en l’absence d’une prise en charge correcte, en milieu spécialisé́, risque de mettre en jeu le pronostic vital. La corticothérapie intraveineuse (CO IV) constitue le traitement médical de première intention de la CAG.L’objectif de notre travail est d’évaluer les facteurs prédictifs de la réponse à la corticothérapie intraveineuse au cours des colites aigues graves.Il s’agit d’une étude observationnelle étalée sur 2 ans, portant sur 27 cas de colites aigues graves colligées au sein de notre service.La CAG a été définie par un score de Lichtiger supérieur à 10.Les données cliniques, biologiques, endoscopiques et radiologiques ont été recueillies et analysés par le logiciel SPSS20.

Author Keywords: Colite aigue grave, maladie inflammatoire chronique intestinale, rectocolite hémorragique, Crohn, traitement.


How to Cite this Article


S. Ouahid, Sanaa Berrag, I. Radouane, F. Nejjari, T. Addioui, Mouna Tamzaourte, and Aziz Aourarh, “Predictive factors of the response to intravenous corticosteroid therapy in severe acute colitis,” International Journal of Innovation and Applied Studies, vol. 29, no. 4, pp. 1027–1029, July 2020.