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International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
 
 
Thursday 15 November 2018

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Association of anthropometric indices of obesity and white blood cell count with arterial stiffness and blood pressure


Volume 9, Issue 1, November 2014, Pages 347–354

 Association of anthropometric indices of obesity and white blood cell count  with arterial stiffness and blood pressure

Muhammad Sajid Mehmood1, Muhammad Mazhar Hussain2, and Saqib Qayum Ahmad3

1 MBBS; Post Graduate Trainee, M.Phil (Physiology), Dept. of Physiology Army Medical College, Rawalpindi/National University of Science and Technology, Islamabad, Pakistan
2 Prof. and Head, Dept. of Physiology, Army Medical College, Rawalpindi/National University of Science and Technology, Islamabad, Pakistan
3 Assistant Prof. of Pathology, Army Medical College, Rawalpindi/National University of Science and Technology, Islamabad, Pakistan

Original language: English

Received 1 August 2014

Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


Background: Obesity induces oxidative stress and inflammation, which may lead to arterial stiffness and hypertension. The relationship of white blood cell count (WBC) and anthropometric indices with arterial stiffness index (ASI) and blood pressure was evaluated in this study.
Methods: Thirty male subjects aged between 35-55 years were selected in each of normotensive, prehypertensive and hypertensive groups. Their weight, height, waist circumference (WC) and hip circumference (HC) were measured according to the WHO guidelines. BMI, waist hip ratio (WHR), waist stature ratio (WSR) and conicity index (CI) were calculated. ASI was calculated from digital volume pulse recorded by photoplethysmography with iWorx-214 physiological interface system. The white blood cell count and differential was done. One way ANOVA followed by Post Hoc Tukey's Test was applied to determine the difference between the groups. Pearson's coefficient was calculated to study the correlation. Statistically, p value < 0.05 was considered significant.
Results: There was statistically significant difference in WHR (0.000), WC (0.003) and ASI (0.000) between the study groups but not BMI (0.223). Amongst the anthropometric measurements, WHR and WC had positive correlation with the systolic and diastolic blood pressure. The WBC and absolute neutrophil count correlated significantly with WHR and WC but not with ASI and blood pressure.
Conclusions: The central obesity is a more robust risk factor for arterial stiffness and blood pressure than BMI. The inflammation may be involved in pathogenesis of visceral obesity and arterial stiffness that may be determined by elevated white blood cell counts.


Author Keywords: Prehypertension, hypertension, Arterial stiffness index, central obesity, inflammation, neutrophil-lymphocyte ratio, cardiovascular diseases.


How to Cite this Article


Muhammad Sajid Mehmood, Muhammad Mazhar Hussain, and Saqib Qayum Ahmad, “Association of anthropometric indices of obesity and white blood cell count with arterial stiffness and blood pressure,” International Journal of Innovation and Applied Studies, vol. 9, no. 1, pp. 347–354, November 2014.